89Zr-ImmunoPET shows therapeutic efficacy of anti-CD20 interferon-α fusion protein in a murine B-cell lymphoma model.
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DOI: 10.1158/1535-7163.mct-21-0732
Abstract: Antibody-mediated tumor delivery of cytokines can overcome limitations of systemic administration (toxicity, short half-lives). Previous work showed improved anti-tumor potency of anti-CD20-interferon alpha (IFNα) fusion proteins in preclinical mouse models of B-cell lymphoma. Although tumor… read more here.
Keywords: rit mifn; fusion protein; rit; 89zr rit ... See more keywords