Sortase-Mediated Site-Specific Conjugation and 89Zr-Radiolabeling of Designed Ankyrin Repeat Proteins for PET.
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DOI: 10.1021/acs.molpharmaceut.2c00136
Abstract: Designed ankyrin repeat proteins (DARPins) are genetically engineered proteins that exhibit high specificity and affinity toward specific targets. Here, the G3-DARPin, which binds the HER2/neu receptor, was site-specifically modified with enzymatic methods and 89Zr-radiolabeled for… read more here.
Keywords: designed ankyrin; sortase; 89zrdfo darpin; darpin ... See more keywords