Abstract LB003: BI 907828: A highly potent MDM2-p53 antagonist suitable for intermittent dose schedules
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DOI: 10.1158/1538-7445.am2023-lb003
Abstract: The E3 ligase MDM2 controls the tumor suppressor function of p53, which is encoded by the TP53gene. Compounds designed to bind to MDM2 preventing its interaction with p53 restore the ability of p53 to combat… read more here.
Keywords: highly potent; mdm2; 907828 highly; potent mdm2 ... See more keywords