Articles with "931 small" as a keyword



Abstract 5041: Translational pharmacokinetic-pharmacodynamic xenograft model for TAK-931, a small molecule cell division cycle 7 (CDC7) kinase inhibitor

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-5041

Abstract: TAK-931 is a small molecule inhibitor of the cell division cycle 7 (CDC7) kinase. As a serine/threonine kinase that contributes to DNA replication and the DNA damage response, CDC7 is hypothesized to be a promising… read more here.

Keywords: cdc7; inhibitor; 931 small; kinase ... See more keywords