A Pretargeted Imaging Strategy for Immune Checkpoint Ligand PD-L1 Expression in Tumor Based on Bioorthogonal Diels-Alder Click Chemistry
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DOI: 10.1007/s11307-019-01441-3
Abstract: Purpose The use of antibodies as tracers requires labeling with isotopes with long half-lives due to their slow pharmacokinetics, which creates prohibitively high radiation dose to non-target organs. Pretargeted methodology could avoid the high radiation… read more here.
Keywords: 99m hynic; hynic peg; chemistry; atezolizumab ... See more keywords