Automatic Striatal ROI Delineation for Semi-quantitative Analysis of 99mTc-TRODAT-1 Brain SPECT Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical and Biological Engineering"
DOI: 10.1007/s40846-020-00530-x
Abstract: Single-photon emission computed tomography (SPECT) imaging, a relatively inexpensive nuclear imaging technique, has been used as a diagnostic tool for Parkinson’s disease (PD). The tracer 99mTc-TRODAT-1 is commonly used in Taiwan, where the imaging cost… read more here.
Keywords: trodat; spect imaging; roi delineation; 99mtc trodat ... See more keywords
99mTc-TRODAT-1 SPECT/CT imaging as a complementary biomarker in the diagnosis of parkinsonian syndromes
Sign Up to like & getrecommendations! Published in 2018 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000000802
Abstract: Introduction Parkinson’s disease (PD) and Parkinson plus syndromes (PPS) are neurodegenerative movement disorders caused by loss of dopamine in the basal ganglia. The diagnosis of both PD and PPS is complex as it is made… read more here.
Keywords: computed tomography; pps; 99mtc trodat; diagnosis ... See more keywords
Reference Values for Dopamine Transporter Imaging With 99mTc-TRODAT-1 in Healthy Subjects and Parkinson’s Disease Patients
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DOI: 10.1097/rlu.0000000000004311
Abstract: Purpose The aim of this study was to evaluate different quantitative indexes of striatum dopamine transporter density in healthy subjects and patients with PD. Patients and Methods Sixty-seven patients, 23 healthy (8 male; 59 ±… read more here.
Keywords: dopamine transporter; index; binding potential; 99mtc trodat ... See more keywords
Incidental detection of probable meningioma in brain scintigraphy using 99mTc-TRODAT-1.
Sign Up to like & getrecommendations! Published in 2017 at "Arquivos de neuro-psiquiatria"
DOI: 10.1590/0004-282x20170004
Abstract: An 84-year-old woman underwent a dopamine transporter (DAT) study to investigate a non-levodopa-responsive parkinsonism. A SPECT brain scan was conducted four hours after intravenous administration of 1110 MBq (megabecquerels) equivalent to 30 mCi (millicuries) of… read more here.
Keywords: scintigraphy; incidental detection; meningioma; brain ... See more keywords
Use of 99mTc-Trodat-1 SPECT to evaluate the efficacy of deep brain stimulation in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2022 at "Hellenic journal of nuclear medicine"
DOI: 10.1967/s002449912512
Abstract: OBJECTIVE This study aimed to explore the availability of striatal dopamine transporter (DAT) after deep brain stimulation (DBS) by single photon emission computed tomography (SPECT) using technetium-99m-labeled tropane derivative (99mTc-Trodat-1). SUBJECTS AND METHODS In this… read more here.
Keywords: deep brain; dbs; brain stimulation; 99mtc trodat ... See more keywords
The Titrated Mannitol Improved Central [99mTc] Tc TRODAT-1 Uptake in an Animal Model—A Clinically Feasible Application
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043773
Abstract: [99mTc]Tc TRODAT-1 is a widely used single photon emission tomography (SPECT) radiopharmaceutical in Asian practice for early detection of central dopaminergic disorders. However, its imaging quality remains sub-optimal. To overcome this problem, mannitol, an osmotic… read more here.
Keywords: clinically feasible; quality; trodat uptake; striatal 99mtc ... See more keywords