Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand To Treat Alzheimer's Disease.
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DOI: 10.1021/acschemneuro.1c00182
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, a multitarget-directed ligands (MTDLs) strategy has been developed to treat AD. We have previously designed and synthesized dimeric tacrine(10)-hupyridone (A10E), a novel tacrine… read more here.
Keywords: alzheimer disease; a10e could; dimeric tacrine; a10e ... See more keywords