Evolution of Melanoma Antigen-A11 (MAGEA11) During Primate Phylogeny
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Evolution"
DOI: 10.1007/s00239-018-9838-8
Abstract: Melanoma antigen-A11 (MAGE-A11) is an X-linked and primate-specific steroid hormone receptor transcriptional coregulator and proto-oncogenic protein whose increased expression promotes the growth of prostate cancer. The MAGEA11 gene is expressed at low levels in normal… read more here.
Keywords: mage a11; evolution; a11; melanoma antigen ... See more keywords
Evaluation of [131I]I- and [177Lu]Lu-DTPA-A11 Minibody for Radioimmunotherapy in a Preclinical Model of PSCA-Expressing Prostate Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-020-01518-4
Abstract: Radioimmunotherapy uses tumor-specific antibodies to deliver therapeutic radionuclides, but hematological toxicity due to the long serum half-life of intact antibodies remains a challenge. We evaluated a smaller antibody fragment, the minibody, with faster kinetics and… read more here.
Keywords: a11; dtpa a11; minibody; 177lu dtpa ... See more keywords