Abstract 5028: The regulation of inflammatory signaling in cancer via A20 phosphorylation
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DOI: 10.1158/1538-7445.am2023-5028
Abstract: A20 is an anti-inflammatory protein with a dual ubiquitin-editing activity. Through its N-terminal ovarian tumor (OTU) domain, A20 negatively regulates NF-ĸB by removing the K63-linked ubiquitin chains on RIP1 that act as platforms for NF-ĸB… read more here.
Keywords: a20; a20 phosphorylation; activity; regulation inflammatory ... See more keywords