Articles with "a2059g mutation" as a keyword



Neisseria gonorrhoeae 23S rRNA A2059G mutation is the only determinant necessary for high-level azithromycin resistance and improves in vivo biological fitness

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Published in 2019 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dky438

Abstract: Objectives The global emergence of Neisseria gonorrhoeae isolates displaying high-level azithromycin resistance is a major concern for the currently recommended azithromycin/ceftriaxone dual therapy. N. gonorrhoeae high-level azithromycin resistance has been associated with an A2059G mutation… read more here.

Keywords: a2059g mutation; level azithromycin; high level; azithromycin resistance ... See more keywords