Differential Innate Immune Signaling in Macrophages by Wild-Type Vaccinia Mature Virus and a Mutant Virus with a Deletion of the A26 Protein
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00767-17
Abstract: ABSTRACT The Western Reserve (WR) strain of mature vaccinia virus contains an A26 envelope protein that mediates virus binding to cell surface laminin and subsequent endocytic entry into HeLa cells. Removal of the A26 protein… read more here.
Keywords: a26; infection; virus; a26 protein ... See more keywords
Structure-guided design of a potent Clostridioides difficile toxin A inhibitor
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1110541
Abstract: Crystal structures of camelid heavy-chain antibody variable domains (VHHs) bound to fragments of the combined repetitive oligopeptides domain of Clostridiodes difficile toxin A (TcdA) reveal that the C-terminus of VHH A20 was located 30 Å away… read more here.
Keywords: difficile toxin; a20; design; terminus ... See more keywords