Rethinking the adenosine-A2AR checkpoint: implications for enhancing anti-tumor immunotherapy.
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DOI: 10.1016/j.coph.2020.07.003
Abstract: Adenosine signaling through A2AR serves as a negative regulator of the immune system. Unique to this suppressive pathway is its ability to impact numerous stromal and immune cells. Additionally, tumors exhibit elevated concentrations of adenosine… read more here.
Keywords: adenosine a2ar; rethinking adenosine; a2ar checkpoint; immunotherapy ... See more keywords