Articles with "a315t transgenic" as a keyword



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Targeting glial cannabinoid CB2 receptors to delay the progression of the pathological phenotype in TDP‐43 (A315T) transgenic mice, a model of amyotrophic lateral sclerosis

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Published in 2019 at "British Journal of Pharmacology"

DOI: 10.1111/bph.14216

Abstract: Cannabinoid CB2 receptors are up‐regulated in reactive microglia in the spinal cord of TDP‐43 (A315T) transgenic mice, an experimental model of amyotrophic lateral sclerosis. To determine whether this up‐regulation can be exploited pharmacologically, we investigated… read more here.

Keywords: cb2 receptors; a315t transgenic; model amyotrophic; cannabinoid cb2 ... See more keywords