Induction of cell death by pyropheophorbide‐α methyl ester‐mediated photodynamic therapy in lung cancer A549 cells
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1012
Abstract: Pyropheophorbide‐α methyl ester (MPPa) was a promising photosensitizer with stable chemical structure, strong absorption, higher tissue selectivity and longer activation wavelengths. The present study investigated the effect of MPPa‐mediated photodynamic treatment on lung cancer A549… read more here.
Keywords: a549 cells; microscopy; pyropheophorbide methyl; cancer ... See more keywords
Role of autophagy in inhibiting the proliferation of A549 cells by type III interferon
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11132
Abstract: Interferons (IFNs) have anti‐viral and anti‐tumour effects. Type III interferon, as a member of the recently discovered interferon family, has been proved to inhibit tumour proliferation and promote the apoptosis of various tumour cells. However,… read more here.
Keywords: a549 cells; proliferation a549; iii interferon; proliferation ... See more keywords
Post-radiation treatment of 3,3'-diselenodipropionic acid augments cell kill by modulating DNA repair and cell migration pathways in A549 cells.
Sign Up to like & getrecommendations! Published in 2023 at "IUBMB life"
DOI: 10.1002/iub.2727
Abstract: Aim of the present study was to test whether ionizing radiation (IR) treatment along with 3,3'-diselenodipropionic acid (DSePA), a redox active organodiselenide achieved better tumor control by suppressing the growth and migration of lung cancer… read more here.
Keywords: dna repair; cell; a549 cells; treatment ... See more keywords
Effect of blue light on the cell viability of A549 lung cancer cells and investigations into its possible mechanism.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300047
Abstract: Blue light has attracted extensive attention as a new potential cancer therapy. Recent studies have indicated that blue light has a significant inhibition effect on A459 cells. However, the effect of light parameters on the… read more here.
Keywords: effect; light; blue light; mechanism ... See more keywords
Antiproliferative effect and autophagy induction of curcumin derivative ZYX02‐Na on the human lung cancer cells A549
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22592
Abstract: At present, a large number of curcumin derivatives had been produced and identified aiming to replace the curcumin in view of its low bioavailability and stability. Here, a novel curcumin derivative ZYX02‐Na was first used… read more here.
Keywords: a549 cells; curcumin derivative; cells a549; derivative zyx02 ... See more keywords
Baicalein inhibits cell proliferation and enhances apoptosis in human A549 cells and benzo(a)pyrene‐induced pulmonary carcinogenesis in mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23053
Abstract: Our current study is done to explore the possible mechanisms to elaborate on the growth inhibitory effect of baicalein (BE) in human lung carcinoma. Initially, BE (25 and 50 µM) treatment for 24 h, suppressed the viability… read more here.
Keywords: cell; apoptosis; benzo pyrene; proliferation ... See more keywords
eEF‐2K knockdown synergizes with STS treatment to inhibit cell proliferation, migration, and invasion via the TG2/ERK pathway in A549 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23158
Abstract: Emerging research has suggested the anticancer potential of tanshinone IIA, the bioactive ingredient isolated from the traditional Chinese herb Salvia miltiorrhiza. However, the molecular mechanism of sodium tanshinone IIA sulfonate (STS) antilung cancer effect is… read more here.
Keywords: proliferation migration; proliferation; treatment; a549 cells ... See more keywords
LncRNA ATB promotes proliferation and metastasis in A549 cells by down‐regulation of microRNA‐494
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26894
Abstract: Lung cancer is a commonly diagnosed disease with poor prognosis. Novel therapeutic targets and deep understanding of the regulatory mechanisms in lung cancer are of great importance. We aimed to figure out the functional roles… read more here.
Keywords: a549 cells; mir 494; a549; proliferation ... See more keywords
Signal transducer and activator of transcription 3 mediates apoptosis inhibition through reducing mitochondrial ROS and activating Bcl‐2 in gemcitabine‐resistant lung cancer A549 cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30133
Abstract: Lung cancer is a leading cause of cancer‐related death worldwide. In this study, we used lung adenocarcinoma cells as a model, as lung adenocarcinoma has the highest mortality rate among all lung cancers. For the… read more here.
Keywords: a549 cells; lung cancer; cancer; gemcitabine resistant ... See more keywords
The miRNA‐149‐5p/MyD88 axis is responsible for ursolic acid‐mediated attenuation of the stemness and chemoresistance of non‐small cell lung cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22891
Abstract: Although the inhibitory roles of ursolic acid (UA) have been established in various tumors, its effects on the stemness of non‐small cell lung cancer (NSCLC) cells are still unclear. Here, we constructed NSCLC cells with… read more here.
Keywords: 149 myd88; stemness; a549 cells; myd88 axis ... See more keywords
Oxidative stress and inflammatory effects in human lung epithelial A549 cells induced by phenanthrene, fluorene, and their binary mixture
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Toxicology"
DOI: 10.1002/tox.23015
Abstract: Low molecular weight‐Polycyclic aromatic hydrocarbons (LMW‐PAHs) are ubiquitous environmental pollutants, which may contribute to respiratory diseases. However, studies of the relative mechanisms are limited. This study aimed to explore the effects of two LMW‐PAHs [phenanthrene… read more here.
Keywords: phe flu; mixture; a549 cells; oxidative stress ... See more keywords