Role and mechanism of chaperones calreticulin and ERP57 in restoring trafficking to mutant HERG-A561V protein
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DOI: 10.3892/ijmm.2021.4992
Abstract: Long QT syndrome type 2 is caused by a mutation in the human-ether-a-go-go-related gene (HERG) gene encoding the rapidly activating delayed rectifier K-current. HERG is a key cell membrane glycoprotein; however, whether the maturation process… read more here.
Keywords: protein; erp57; a561v; crt ... See more keywords