Characterization of G-Quadruplexes in Enterovirus A71 Genome and Their Interaction with G-Quadruplex Ligands
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00460-22
Abstract: G-quadruplex is a stable nucleic acid secondary structure formed by the folding of guanine rich nucleic acid. The important regulatory function of G-quadruplex makes it an attractive target of antiviral effect. ABSTRACT Human enteroviruses cause… read more here.
Keywords: a71 genome; human enteroviruses; quadruplex ligands; nucleic acid ... See more keywords
Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091067
Abstract: Enterovirus A71 (EV-A71) infection is a major cause of hand, foot, and mouth disease (HFMD), which may be occasionally associated with severe neurological complications. There is currently a lack of treatment options for EV-A71 infection.… read more here.
Keywords: genome replication; replication; a71 genome; anti a71 ... See more keywords