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   Articles with "aaa" as a keyword



The Molecular Mechanisms of Bergapten Against Abdominal Aortic Aneurysm: Evidence From Network Pharmacology, Molecular Docking/Dynamics, and Experimental Validation

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recommendations! Published in 2025 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.70029

Abstract: This study endeavors to assess the potential protective role of bergapten (BP) in mitigating abdominal aortic aneurysm (AAA) and to decipher the underlying mechanisms and molecular targets. Network pharmacology was utilized to search for potential… read more here.

Keywords: molecular docking; network pharmacology; pharmacology; abdominal aortic ... See more keywords

Screening of circulating microRNA biomarkers for prevalence of abdominal aortic aneurysm and aneurysm growth.

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recommendations! Published in 2017 at "Atherosclerosis"

DOI: 10.1016/j.atherosclerosis.2016.11.007

Abstract: BACKGROUND AND AIMS MicroRNA (miR) are important regulators of gene expression and biological processes and have recently been suggested as possible biomarkers for abdominal aortic aneurysm (AAA) disease. The aim of the present study was… read more here.

Keywords: aneurysm; aortic aneurysm; expression; abdominal aortic ... See more keywords

Long-term outcomes after repair of symptomatic abdominal aortic aneurysms.

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recommendations! Published in 2018 at "Journal of vascular surgery"

DOI: 10.1016/j.jvs.2018.02.036

Abstract: OBJECTIVES Previous studies have reported increased perioperative mortality of nonruptured symptomatic abdominal aortic aneurysms (Sx-AAA) compared with asymptomatic elective AAA (E-AAA) repairs, but no long-term-outcomes have been reported. We sought to compare long-term outcomes of… read more here.

Keywords: aaa aaa; long term; year; aaa ... See more keywords

Rupture of abdominal aortic aneurysm between early and late phases of enhanced computed tomography

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recommendations! Published in 2017 at "Journal of Vascular Surgery Cases and Innovative Techniques"

DOI: 10.1016/j.jvscit.2016.07.004

Abstract: Ruptured abdominal aortic aneurysm (RAAA) is fatal in >80% of cases, and mortality is as high as 42% of those who survive RAAA and undergo surgery (42%). Sensitivity and specificity of computed tomography (CT) for… read more here.

Keywords: computed tomography; aneurysm early; aortic aneurysm; rupture abdominal ... See more keywords
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Identification of patients with primary ovarian insufficiency caused by autoimmunity.

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recommendations! Published in 2017 at "Reproductive biomedicine online"

DOI: 10.1016/j.rbmo.2017.06.010

Abstract: Autoimmune pathogenesis is responsible for a subset of primary ovarian insufficiency (POI) cases. The significance of autoantibodies for POI, however, remains unclear. A total of 250 women with idiopathic POI and 256 age-matched healthy women… read more here.

Keywords: antibody; antibody anti; primary ovarian; ovarian insufficiency ... See more keywords
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Effective Modified Xanthan Gum Fluid Loss Agent for High-Temperature Water-Based Drilling Fluid and the Filtration Control Mechanism

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recommendations! Published in 2021 at "ACS Omega"

DOI: 10.1021/acsomega.1c02617

Abstract: Xanthan gum (XG) was widely used as an oilfield chemical treatment agent because of its environmental protection and diverse functions. With the increased drilling depth and formation complexity, the shortcomings such as poor solubility and… read more here.

Keywords: temperature; rheology; high temperature; aaa ... See more keywords

Targeted Drug Delivery of Microbubble to Arrest Abdominal Aortic Aneurysm Development: A Simulation Study Towards Optimized Microbubble Design

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-62410-3

Abstract: Abdominal aortic aneurysm (AAA) is an irreversible bulge in the artery with higher prevalence among the elderlies. Increase of the aneurysm diameter by time is a fatal phenomenon which will lead to its sidewall rupture.… read more here.

Keywords: aneurysm; drug delivery; delivery; drug ... See more keywords

Implicit screening of abdominal aortic aneurysms among veterans using lumbar spine MRI.

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recommendations! Published in 2024 at "Current problems in diagnostic radiology"

DOI: 10.1067/j.cpradiol.2024.01.022

Abstract: BACKGROUND Early detection of abdominal aortic aneurysms (AAAs) is critical given the high morbidity and mortality of a ruptured aneurysm. Screening ultrasound is recommended for men 65 and 75 years of age with a smoking… read more here.

Keywords: history; abdominal aortic; spine; aortic aneurysms ... See more keywords

POU class 2 homeobox associating factor 1 (POU2AF1) participates in abdominal aortic aneurysm enlargement based on integrated bioinformatics analysis.

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recommendations! Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1990822

Abstract: Abdominal aortic aneurysm (AAA) is life-threatening, its natural course is progressively sac expansion and rupture. Elegant studies have been conducted to investigate the molecular markers associated with AAA growth and expansion, this topic however, still… read more here.

Keywords: large aaa; pou2af1; analysis; aortic aneurysm ... See more keywords

Targeting Mitochondrial Fission as a Potential Therapeutic for Abdominal Aortic Aneurysm.

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recommendations! Published in 2020 at "Cardiovascular research"

DOI: 10.1093/cvr/cvaa133

Abstract: AIMS Angiotensin II is a potential contributor to the development of abdominal aortic aneurysm (AAA). In aortic vascular smooth muscle cells, exposure to angiotensin II induces mitochondrial fission via dynamin-related protein 1 (Drp1). However, pathophysiological… read more here.

Keywords: fission; smooth muscle; mitochondrial fission; abdominal aortic ... See more keywords

Erythropoietin promotes abdominal aortic aneurysms in mice through angiogenesis and inflammatory infiltration

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recommendations! Published in 2021 at "Science Translational Medicine"

DOI: 10.1126/scitranslmed.aaz4959

Abstract: Erythropoietin dose-dependently induces abdominal aortic aneurysm in mice via JAK2/STAT5 signaling, even without angiotensin II infusion. Erythropoietin and AAA Abdominal aortic aneurysm (AAA) is a common vascular disease, but its pathogenesis has not been fully… read more here.

Keywords: erythropoietin; formation; epo; mice ... See more keywords