Pharmacologic inhibition by spironolactone attenuates experimental abdominal aortic aneurysms
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1101389
Abstract: Background Abdominal aortic aneurysms (AAA) are characterized by vascular inflammation and remodeling that can lead to aortic rupture resulting in significant mortality. Pannexin-1 channels on endothelial cells (ECs) can modulate ATP secretion to regulate the… read more here.
Keywords: aortic aneurysms; aaa model; spironolactone; abdominal aortic ... See more keywords