Effects of rhein and Rheum palmatum L. extract on the pharmacokinetics and tissue distribution of aristolochic acid I and its demethylated metabolite in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113537
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Aristolochic acid nephropathy (AAN) is a kidney disease caused by the administration of plants containing aristolochic acids (AAs). Aristolochic acid I (AAI) is the main toxic component in AAs. Organic anion transporters (OATs)… read more here.
Keywords: tissue distribution; pharmacokinetics tissue; aai; aai aaia ... See more keywords
Glycine N-methyltransferase inhibits aristolochic acid nephropathy by increasing CYP3A44 and decreasing NQO1 expression in female mouse hepatocytes
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22298-6
Abstract: Plants containing aristolochic acids (AA) are nephrotoxins. Glycine N-methyltransferase (GNMT) acts to bind environmental toxins such as benzo(a)pyrene and aflatoxin B1, translocate into nucleus, and alter hepatic metabolism. This study aims to determine the role… read more here.
Keywords: glycine methyltransferase; increasing cyp3a44; induced nephropathy; gnmt ... See more keywords
P51: REVIEW OF THE USE OF ARENALINE AUTOINJECTORS (AAI) IN NSW DEPARTMENT OF EDUCATION SCHOOLS IN TERMS 1 AND 2 2017
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DOI: 10.1111/imj.51_13578
Abstract: In response to these episodes, 48 AAI’s were used. Personal prescribed AAI were used in 25 cases, one student was given 2 personal AAI. General use AAI were used in 20 cases, including 2 students… read more here.
Keywords: review use; aai used; p51 review; aai ... See more keywords
Benefit of educational intervention on Autoinjector Technique for caregivers and paediatric patients with food allergies: A literature review.
Sign Up to like & getrecommendations! Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i5.582
Abstract: BACKGROUND AND OBJECTIVE The incidence of food allergy among children is on the rise. Children who are diagnosed with a food allergy receive long-term treatment for allergy management from allergy specialists, nurses and dieticians. This… read more here.
Keywords: paediatric patients; food; educational intervention; aai ... See more keywords
Management of Children With Food-Induced Anaphylaxis: A Cross-Sectional Survey of Parental Knowledge, Attitude, and Practices
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.886551
Abstract: Background Anaphylaxis is a life-threatening event, but it is frequently undertreated in pediatric patients with food allergies. Previous studies showed that auto-injectable adrenaline (AAI) is underused by patients and parents. This is especially troubling since… read more here.
Keywords: food; survey; knowledge; aai ... See more keywords
Restoring the top-of-atmosphere reflectance during solar eclipses: aproof of concept with the UV Absorbing Aerosol Index measured byTROPOMI
Sign Up to like & getrecommendations! Published in 2020 at "Atmospheric Chemistry and Physics"
DOI: 10.5194/acp-2020-1172
Abstract: Abstract. Solar eclipses reduce the measured top-of-atmosphere (TOA) reflectances as derived by Earth observation satellites, because the solar irradiance that is used to compute these reflectances is commonly measured before the start of the eclipse.… read more here.
Keywords: shadow; obscuration; reflectance; solar eclipses ... See more keywords