GPCR Pharmacological Profiling of Aaptamine from the Philippine Sponge Stylissa sp. Extends Its Therapeutic Potential for Noncommunicable Diseases
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DOI: 10.3390/molecules26185618
Abstract: We report the first isolation of the alkaloid aaptamine from the Philippine marine sponge Stylissa sp. Aaptamine possessed weak antiproliferative activity against HCT116 colon cancer cells and inhibited the proteasome in vitro at 50 µM.… read more here.
Keywords: noncommunicable diseases; activity; sponge stylissa; aaptamine philippine ... See more keywords