AAV cis-regulatory sequences are correlated with ocular toxicity
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DOI: 10.1073/pnas.1821000116
Abstract: Significance Adeno-associated viral (AAV) gene therapy is becoming an important therapeutic modality, especially for ocular diseases, due to its efficiency of gene delivery and relative lack of pathogenicity. However, AAV sometimes can cause inflammation and… read more here.
Keywords: toxicity; aav cis; regulatory sequences; cis regulatory ... See more keywords