Downregulation of pathways implicated in liver inflammation and tumorigenesis of glycogen storage disease type Ia mice receiving gene therapy
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DOI: 10.1093/hmg/ddx097
Abstract: &NA; Glycogen storage disease type Ia (GSD‐Ia) is characterized by impaired glucose homeostasis and long‐term risks of hepatocellular adenoma (HCA) and carcinoma (HCC). We have shown that the non‐tumor‐bearing (NT), recombinant adeno‐associated virus (rAAV) vector‐treated… read more here.
Keywords: aav mice; signaling pathways; glycogen storage; mice ... See more keywords