Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation
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DOI: 10.3389/fimmu.2019.03110
Abstract: Pre-existing immunity to AAV capsid may compromise the safety and efficiency of rAAV-mediated gene transfer in patients. Anti-capsid cytotoxic immune responses have proven to be a challenge to characterize because of the scarcity of circulating… read more here.
Keywords: specific cd8; cd8; cd8 cells; aav8 ... See more keywords