AAV9-mediated engineering of autotransplanted kidney of non-human primates
Sign Up to like & getrecommendations! Published in 2017 at "Gene Therapy"
DOI: 10.1038/gt.2017.21
Abstract: Ex vivo gene transfer to the graft before transplantation is an attractive option for circumventing systemic side effects of chronic antirejection therapy. Gene delivery of the immunomodulatory protein cytotoxic T-lymphocyte-associated protein 4–immunoglobulin (CTLA4-Ig) prevented chronic… read more here.
Keywords: non human; kidney non; mediated engineering; human primates ... See more keywords
Neurologic Recovery in MPS I and MPS II Mice by AAV9-Mediated Gene Transfer to the CNS after the Development of Cognitive Dysfunction.
Sign Up to like & getrecommendations! Published in 2022 at "Human gene therapy"
DOI: 10.1089/hum.2022.162
Abstract: The mucopolysaccharidoses (MPS) are a group of recessively inherited conditions caused by deficiency of lysosomal enzymes essential to the catabolism of glycosaminoglycans. MPS I is caused by deficiency of the lysosomal enzyme alpha-L-iduronidase (IDUA), while… read more here.
Keywords: mps mps; gene transfer; aav9 mediated; gene ... See more keywords