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Published in 2020 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520620666200728125356
Abstract: BACKGROUND AND OBJECTIVE Histone deacetylases (HDACs) are important therapeutic targets for many types of human cancers. A derivative of valproic acid, N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA), has antiproliferative properties on some cancer cell lines and inhibits the HDAC1…
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Keywords:
u87 cells;
antiangiogenic properties;
hydroxyphenyl propylpentanamide;
aavpa antiproliferative ... See more keywords