What monomeric nucleotide binding domains can teach us about dimeric ABC proteins
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13921
Abstract: The classic conceptualization of ATP binding cassette (ABC) transporter function is an ATP‐dependent conformational change coupled to transport of a substrate across a biological membrane via the transmembrane domains (TMDs). The binding of two ATP… read more here.
Keywords: nbd dimerization; nucleotide binding; binding domains; abc proteins ... See more keywords
A twist in the ABC: regulation of ABC transporter trafficking and transport by FK506‐binding proteins
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13983
Abstract: Post‐transcriptional regulation of ATP‐binding cassette (ABC) proteins has been so far shown to encompass protein phosphorylation, maturation, and ubiquitination. Yet, recent accumulating evidence implicates FK506‐binding proteins (FKBPs), a type of peptidylprolyl cis–trans isomerase (PPIase) proteins,… read more here.
Keywords: binding proteins; abc transporter; abc; fk506 binding ... See more keywords
Novel EGFR‐MAPK kinase and ABC transporter inhibitors for HepG2 resistant to Erlotinib
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.22023
Abstract: Hepatocellular carcinoma (HCC) is the third‐leading cause of cancer death in the world, with outlook for most patients having a 5‐year survivability of less than 5%. In a previous study from our laboratory, novel estrone… read more here.
Keywords: resistant erlotinib; hepg2 resistant; inhibitors hepg2; mma102 ... See more keywords
The human ATP‐binding cassette (ABC) transporter superfamily
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24418
Abstract: The ATP‐binding cassette (ABC) transporter superfamily comprises membrane proteins that efflux various substrates across extra‐ and intracellular membranes. Mutations in ABC genes cause 21 human disorders or phenotypes with Mendelian inheritance, including cystic fibrosis, adrenoleukodystrophy,… read more here.
Keywords: atp binding; binding cassette; abc transporter; abc ... See more keywords
Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02395-9
Abstract: Several ATP-binding cassette (ABC) proteins reduce intracellular concentrations of antitumor drugs and hence weaken the response of cancer cells to chemotherapy. Accordingly, the inhibition of these export pumps constitutes a promising strategy to chemosensitize highly… read more here.
Keywords: hepatocellular carcinoma; cells sorafenib; export pumps; caryophyllene oxide ... See more keywords
Introducing three new ABC Editors
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-01706-4
Abstract: At ABC, we recently had the opportunity to bring three new Editors onto our team: Antje Baeumner, Maria Moreno-Bondi, and Luigi Mondello. These new Editors are based in the key ABC co-owner-society countries of Germany,… read more here.
Keywords: new editors; research; three new; chemistry ... See more keywords
Response to a letter to the editor concerning “Giant Cell Reparative Granuloma of the Scapula: report of a case and literature review”
Sign Up to like & getrecommendations! Published in 2019 at "Skeletal Radiology"
DOI: 10.1007/s00256-019-03326-6
Abstract: We read with interest the letter to the editor regarding our manuscript on giant cell reparative granuloma (GCRG) of the scapula. The author commented that some relevant aspects have been omitted in the description and… read more here.
Keywords: giant cell; gcrg; abc; case ... See more keywords
A lavender ABC transporter confers resistance to monoterpene toxicity in yeast
Sign Up to like & getrecommendations! Published in 2018 at "Planta"
DOI: 10.1007/s00425-018-3064-x
Abstract: Main conclusionFunctional expression of a multidrug resistance-type ABC transporter from Lavandulaangustifolia improved yeast resistance to geraniol, a monoterpene constituent of lavender essential oil.Plant ATP-binding cassette (ABC) transporters are a large family of membrane proteins involved… read more here.
Keywords: abc transporter; lavender; abc; yeast ... See more keywords
Island artificial bee colony for global optimization
Sign Up to like & getrecommendations! Published in 2020 at "Soft Computing"
DOI: 10.1007/s00500-020-04760-8
Abstract: This paper proposes an efficient version of artificial bee colony (ABC) algorithm based on the island model concepts. The new version is called the island artificial bee colony ( i ABC) algorithm. It uses the… read more here.
Keywords: bee colony; test functions; abc; island ... See more keywords
Enumeration of conformers for octahedral $$[\hbox {MX(AB)}_{5}]$$[MX(AB)5] and [$$\hbox {MX(ABC)}_{5}$$MX(ABC)5] complexes on the basis of computational group theory
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Mathematical Chemistry"
DOI: 10.1007/s10910-017-0751-y
Abstract: Conformers of [$$\hbox {MX(AB)}_{5}$$MX(AB)5] and [$$\hbox {MX(ABC)}_{5}$$MX(ABC)5] complexes have been enumerated on the basis of computational group theory, where M is the central metal, X is the monoatomic ligand, and AB and ABC are the… read more here.
Keywords: hbox hbox; hbox abc; abc; abc complexes ... See more keywords
Mechanically Unfolded Titin Immunoglobulin Domains Refold Faster and More Accurately in Presence of Chaperone Alpha-B-Crystallin
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.263
Abstract: The spring region of the giant muscle protein titin contains many immunoglobulin-like (Ig) domains, which unfold and refold under low (physiological) stretch forces. Small heat shock proteins such as alphaB-crystallin (aBC) translocate under physiological or… read more here.
Keywords: refolded fraction; titin; presence; abc ... See more keywords