Application of CRISPR/Cas9 System to Reverse ABC-Mediated Multidrug Resistance.
Sign Up to like & getrecommendations! Published in 2021 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.0c00627
Abstract: Multidrug resistance (MDR) is the main obstacle in cancer chemotherapy. ATP-binding cassette (ABC) transporters can transport a wide range of antitumor drugs out of cells, which is the most common reason in the development of… read more here.
Keywords: abc mediated; crispr cas9; resistance; cas9 system ... See more keywords