What monomeric nucleotide binding domains can teach us about dimeric ABC proteins
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13921
Abstract: The classic conceptualization of ATP binding cassette (ABC) transporter function is an ATP‐dependent conformational change coupled to transport of a substrate across a biological membrane via the transmembrane domains (TMDs). The binding of two ATP… read more here.
Keywords: nbd dimerization; nucleotide binding; binding domains; abc proteins ... See more keywords
Inventory of ABC proteins and their putative role in salt and drug tolerance in Debaryomyces hansenii.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.07.029
Abstract: ATP-binding cassette (ABC) is one of the largest superfamily of proteins, which are ubiquitously present, performing variety of cellular functions. These proteins as drug transporters have been enticing substantial consideration because of their clinical importance.… read more here.
Keywords: abc proteins; drug; drug tolerance; salt drug ... See more keywords
Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac058
Abstract: Abstract The first member of the pleuromutilin (PLM) class suitable for systemic antibacterial chemotherapy in humans recently entered clinical use, underscoring the need to better understand mechanisms of PLM resistance in disease-causing bacterial genera. Of… read more here.
Keywords: sal; type abc; abc proteins; resistance ... See more keywords
Phylogenetic analysis of the ATP-binding cassette proteins suggests a new ABC protein subfamily J in Aedes aegypti (Diptera: Culicidae)
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-06873-8
Abstract: We performed an in-depth analysis of the ABC gene family in Aedes aegypti (Diptera: Culicidae), which is an important vector species of arthropod-borne viral infections such as chikungunya, dengue, and Zika. Despite its importance, previous… read more here.
Keywords: aedes aegypti; diptera culicidae; analysis; abc proteins ... See more keywords
Filling the Gap: Functional Clustering of ABC Proteins for the Investigation of Hormonal Transport in planta
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2019.00422
Abstract: Plant hormones regulate a myriad of plant processes, from seed germination to reproduction, from complex organ development to microelement uptake. Much has been discovered on the factors regulating the activity of phytohormones, yet there are… read more here.
Keywords: hormonal transport; abc proteins; plant; functional clustering ... See more keywords