A twist in the ABC: regulation of ABC transporter trafficking and transport by FK506‐binding proteins
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13983
Abstract: Post‐transcriptional regulation of ATP‐binding cassette (ABC) proteins has been so far shown to encompass protein phosphorylation, maturation, and ubiquitination. Yet, recent accumulating evidence implicates FK506‐binding proteins (FKBPs), a type of peptidylprolyl cis–trans isomerase (PPIase) proteins,… read more here.
Keywords: binding proteins; abc transporter; abc; fk506 binding ... See more keywords
ABC transporter activity is affected by the size of lipid nanodiscs
Sign Up to like & getrecommendations! Published in 2025 at "Febs Letters"
DOI: 10.1002/1873-3468.15096
Abstract: Lipid nanodiscs have become a widely used approach for studying membrane proteins thanks to several advantages they offer. They have been especially useful for studying ABC transporters, despite the growing concern about the possible restriction… read more here.
Keywords: lipid nanodiscs; transporter activity; size; activity ... See more keywords
Comparative genomic analysis of ABC transporter genes in Tenebrio molitor and four other tenebrionid beetles (Coleoptera: Tenebrionidea).
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21916
Abstract: ATP-binding cassette (ABC) transporters, one of the largest transmembrane protein families, transport a diverse number of substate across membranes. Details of their diverse physiological functions have not been established. Here, we identified 87 ABC transporter… read more here.
Keywords: tenebrio molitor; abc transporter; transporter genes;
The human ATP‐binding cassette (ABC) transporter superfamily
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24418
Abstract: The ATP‐binding cassette (ABC) transporter superfamily comprises membrane proteins that efflux various substrates across extra‐ and intracellular membranes. Mutations in ABC genes cause 21 human disorders or phenotypes with Mendelian inheritance, including cystic fibrosis, adrenoleukodystrophy,… read more here.
Keywords: atp binding; binding cassette; abc transporter; abc ... See more keywords
A lavender ABC transporter confers resistance to monoterpene toxicity in yeast
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DOI: 10.1007/s00425-018-3064-x
Abstract: Main conclusionFunctional expression of a multidrug resistance-type ABC transporter from Lavandulaangustifolia improved yeast resistance to geraniol, a monoterpene constituent of lavender essential oil.Plant ATP-binding cassette (ABC) transporters are a large family of membrane proteins involved… read more here.
Keywords: abc transporter; lavender; abc; yeast ... See more keywords
The ABC transporter Snu and the extracellular protein Snsl cooperate in the formation of the lipid-based inward and outward barrier in the skin of Drosophila.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2017.12.003
Abstract: Lipids in extracellular matrices (ECM) contribute to barrier function and stability of epithelial tissues such as the pulmonary alveoli and the skin. In insects, skin waterproofness depends on the outermost layer of the extracellular cuticle… read more here.
Keywords: barrier; abc transporter; snu extracellular; extracellular protein ... See more keywords
Derivative of 5-cyano-6-phenylpyrimidin antagonizes ABCB1- and ABCG2-mediated multidrug resistance.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172611
Abstract: Multidrug resistance (MDR) leads to inadequate response to chemotherapy and cause failure in cancer treatment. One of the targeted approaches to overcome MDR in cancer cells is interfering or inhibiting ATP binding cassette (ABC) transporters.… read more here.
Keywords: transporter subfamily; mdr; abc transporter; cyano phenylpyrimidin ... See more keywords
The E-helix is a central core in a conserved helical bundle involved in nucleotide binding and transmembrane domain intercalation in the ABC transporter superfamily.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.01.030
Abstract: ABC transporter proteins are involved in active transport, both in prokaryotes and eukaryotes. Sequence analysis of nucleotide binding domains (NBDs) of ABC proteins from all taxa revealed a well-conserved new motif having the signature: xT/ShxE/DNhxF,… read more here.
Keywords: nucleotide binding; abc transporter; domain; helix central ... See more keywords
Processing and secretion of non-cognate bacteriocins by EnkT, an ABC transporter from a multiple-bacteriocin producer, Enterococcus faecium NKR-5-3.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2020.07.017
Abstract: EnkT is an ATP-binding cassette (ABC) transporter produced by Enterococcus faecium NKR-5-3, which is responsible for the secretion of multiple bacteriocins; enterocins NKR-5-3A, C, D, and Z (Ent53A, C, D, and Z). EnkT has been… read more here.
Keywords: bacteriocin; cognate; abc transporter; non cognate ... See more keywords
Immunization with the basic membrane protein (BMP) family ABC transporter elicits protection against Enterococcus faecium in a murine infection model.
Sign Up to like & getrecommendations! Published in 2019 at "Microbes and infection"
DOI: 10.1016/j.micinf.2019.09.002
Abstract: Enterococcus faecium is evolving as a multi-resistant pathogen causing infections with high morbidity and mortality. A protective vaccine against E. faecium is lacking up till now. ATP-binding cassette (ABC) transporter proteins have important functions in… read more here.
Keywords: protein; abc transporter; bmp; faecium ... See more keywords
The Lpt ABC transporter for lipopolysaccharide export to the cell surface.
Sign Up to like & getrecommendations! Published in 2019 at "Research in microbiology"
DOI: 10.1016/j.resmic.2019.07.005
Abstract: The surface of the outer membrane of Gram-negative bacteria is covered by a tightly packed layer of lipopolysaccharide molecules which provide a barrier against many toxic compounds and antibiotics. Lipopolysaccharide, synthesized in the cytoplasm, is… read more here.
Keywords: cell surface; surface; membrane; abc transporter ... See more keywords