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   Articles with "abca1 expression" as a keyword



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Glucagon-like peptide-1 contributes to increases ABCA1 expression by downregulating miR-758 to regulate cholesterol homeostasis.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.02.126

Abstract: Abnormal regulation of lipid metabolism is associated with type 2 diabetes mellitus (T2DM). GLP-1 as a new treatment for T2DM, has unique effects in modulating cholesterol homeostasis. However, the mechanism of this effect is largely… read more here.

Keywords: mir 758; abca1 expression; cholesterol homeostasis; cholesterol ... See more keywords
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The lipid moiety 7‐ketocholesteryl‐9‐carboxynonanoate mediates binding interaction of oxLDL to LOX‐1 and upregulates ABCA1 expression through PPAR&ggr;

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recommendations! Published in 2017 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.03.024

Abstract: Aim: Lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1), a specific membrane receptor for oxidized low‐density lipoprotein (oxLDL), plays a crucial role in atherosclerosis progression. The aim of this study was to elucidate the role of 7‐ketocholesteryl‐9‐carboxynonanoate… read more here.

Keywords: ppar ggr; abca1 expression; lox;
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Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367

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recommendations! Published in 2018 at "Mediators of Inflammation"

DOI: 10.1155/2018/8907143

Abstract: We previously reported that propofol upregulated the expression of ATP-binding cassette transporter subfamily A member 1 (ABCA1) via peroxisome proliferator-activated receptor gamma/liver X receptor in macrophage-derived foam cells. Here, we provide evidence that in addition… read more here.

Keywords: propofol; expression; proinflammatory cytokine; abca1 expression ... See more keywords
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ABCA1 Expression Is Upregulated in an EMT in Breast Cancer Cell Lines via MYC-Mediated De-Repression of Its Proximal Ebox Element

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recommendations! Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10030581

Abstract: The ATP-Binding Cassette transporter A1 (ABCA1) reverse cholesterol transport channel has been associated with a number of phenotypes in breast cancer, including reduced proliferation and increased metastatic capacity. It is induced in an epithelial–mesenchymal transition… read more here.

Keywords: abca1 expression; expression; breast cancer; myc ... See more keywords
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Effects of 2-Methoxyestradiol, a Main Metabolite of Estradiol on Hepatic ABCA1 Expression in HepG2 Cells

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recommendations! Published in 2022 at "Nutrients"

DOI: 10.3390/nu14020288

Abstract: ATP-binding cassette transporter A1 (ABCA1) is a key regulator of lipid efflux, and the absence of ABCA1 induces hepatic lipid accumulation, which is one of the major causes of fatty liver. 2-Methoxyestradiol (2-ME2) has been… read more here.

Keywords: abca1 expression; expression; me2; foxo1 ... See more keywords