Exosomes from CD133+ cells carrying circ‐ABCC1 mediate cell stemness and metastasis in colorectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29600
Abstract: Colorectal cancer (CRC), a fatal tumor, has been diagnosed as one of the most prevalent types of cancers globally, inducing multiple cancer‐linked deaths. Mounting evidence has revealed that circular RNA (circRNA) elicits a regulatory impact… read more here.
Keywords: metastasis; cell stemness; abcc1; circ abcc1 ... See more keywords
Adenosine triphosphate Binding Cassette subfamily C member 1 (ABCC1) overexpression reduces APP processing and increases alpha- versus beta-secretase activity, in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Biology open"
DOI: 10.1242/bio.054627
Abstract: The organic anion transporter Adenosine triphosphate Binding Cassette subfamily C member 1 (ABCC1), also known as MRP1, has been demonstrated in murine models of Alzheimer's disease (AD) to export amyloid beta (Abeta) from the endothelial… read more here.
Keywords: abcc1; triphosphate binding; adenosine triphosphate; beta ... See more keywords
Circular RNA circ-CD44 regulates chemotherapy resistance by targeting the miR-330-5p/ABCC1 axis in colorectal cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-516
Abstract: BACKGROUND Colorectal cancer (CRC) is a common malignant tumor worldwide, ranking fourth for incidence. Recently, circular RNAs (circRNAs) have been demonstrated to play a key role in chemotherapy resistance to CRC treatment. Therefore, the role… read more here.
Keywords: cd44; chemotherapy resistance; abcc1; circ cd44 ... See more keywords
Circ-ABCC1 enhances radioresistance of breast cancer cells via miR-627-5p/ABCC1 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.10.29
Abstract: Adjuvant radiotherapy represents the standard of care for breast cancer (BC) following breast-conserving surgery. Tumor recurrence after radiotherapy, attributed to acquired radioresistance, has been a haunting and intractable problem. Therefore, preventions from tumor recurrence are… read more here.
Keywords: abcc1; mir 627; breast; circ abcc1 ... See more keywords
ABCC1 is a predictive biomarker for prognosis and therapy in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202304_32143
Abstract: OBJECTIVE Liver neoplasm is one of the most fatal malignancies worldwide, among which hepatocellular carcinoma (HCC) (MIM #114550, https://omim.org/) is the most prevalent type. ABCC1 (MIM *158343) is a membrane-bound protein that relies on ATP… read more here.
Keywords: hepatocellular carcinoma; abcc1; prognosis; hcc ... See more keywords
Encorafenib Acts as a Dual-Activity Chemosensitizer through Its Inhibitory Effect on ABCC1 Transporter In Vitro and Ex Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122595
Abstract: Encorafenib (LGX818, trade name Braftovi), a novel BRAF inhibitor, has been approved for the treatment of melanoma and colorectal cancer. In the present work, we evaluated encorafenib’s possible antagonistic effects on the pharmacokinetic mechanisms of… read more here.
Keywords: vitro vivo; abcc1; abcc1 transporter; activity ... See more keywords