Genetic engineering of novel super long-acting Exendin-4 chimeric protein for effective treatment of metabolic and cognitive complications of obesity.
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DOI: 10.1016/j.biomaterials.2020.120250
Abstract: A common bottleneck challenge for many therapeutic proteins lies in their short plasma half-lives, which often makes the treatment far less compliant or even disables achieving sufficient therapeutic efficacy. To address this problem, we introduce… read more here.
Keywords: fusion; treatment; abd aff; strategy ... See more keywords