Predicting outcome in abdominal sepsis: putting the puzzle together
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12779
Abstract: Acquired muscular weakness and muscle wasting are frequently observed in critically ill patients, especially after a prolonged time in the intensive care unit (ICU). Patients with severe pulmonary and/or abdominal infections are at increased risk… read more here.
Keywords: sepsis; critical illness; muscle; treatment ... See more keywords
Management of the open abdomen using negative pressure wound therapy with instillation in severe abdominal sepsis
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2016.11.024
Abstract: Highlights • Intra-abdominal sepsis remains one the leading causes of mortality in the SICU .• Multiple surgical approaches have been introduced as part of the management of the open abdomen with varying results.• Negative pressure… read more here.
Keywords: sepsis; open abdomen; pressure wound; negative pressure ... See more keywords
Comparison of Duration and Empiric Antibiotic Choice of Post-Operative Treatment in Abdominal Sepsis.
Sign Up to like & getrecommendations! Published in 2022 at "Surgical infections"
DOI: 10.1089/sur.2021.344
Abstract: Background: Although abdominal foci are the second most common source of sepsis, only few studies focus on the optimal length of post-operative antibiotic therapy in critically ill patients with abdominal sepsis. The aim of this… read more here.
Keywords: sepsis; antibiotic therapy; abdominal sepsis; post operative ... See more keywords
THE EFFECTS OF DNASE I AND LOW-MOLECULAR-WEIGHT HEPARIN IN A MURINE MODEL OF POLYMICROBIAL ABDOMINAL SEPSIS
Sign Up to like & getrecommendations! Published in 2023 at "Shock"
DOI: 10.1097/shk.0000000000002095
Abstract: ABSTRACT Introduction: Cell-free DNA (CFDNA) has emerged as a prognostic biomarker in patients with sepsis. Circulating CFDNA is hypothesized to be associated with histones in the form of nucleosomes. In vitro, DNA activates coagulation and… read more here.
Keywords: dnase; combination; abdominal sepsis; mice ... See more keywords
Clinical Characteristics and Predictors of Mortality Differ Between Pulmonary and Abdominal Sepsis.
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DOI: 10.1097/shk.0000000000002151
Abstract: BACKGROUND Pulmonary and abdominal sepsis have pathophysiologically distinct phenotypes. This study aimed to compare their clinical characteristics and predictors of mortality. METHODS In this multicenter retrospective trial, 1,359 adult patients who fulfilled the Sepsis-3 criteria… read more here.
Keywords: sepsis; abdominal sepsis; mortality; day mortality ... See more keywords
Machine learning and murine models explain failures of clinical sepsis trials
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003691
Abstract: All sepsis is not the same. There are differences in the inflammatory responses that result from intra-abdominal sepsis and gram-negative pneumonia models. HAT is beneficial in intra-abdominal sepsis but not in the pulmonary sepsis model.… read more here.
Keywords: sepsis; abdominal sepsis; sepsis trials; pna ... See more keywords
Blocking purinergic signaling alters platelet and macrophage crosstalk and phagocytic ability in the peritoneal cavity during intra-abdominal sepsis
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5785322
Abstract: Intra-abdominal sepsis is a life-threatening complex syndrome caused by dysregulation of the host response to infection and is one of the major complications of intra-abdominal surgery. To date, only supportive therapies such as ventilation support,… read more here.
Keywords: sepsis; surgery; p2y1 p2y12; abdominal sepsis ... See more keywords
Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study.
Sign Up to like & getrecommendations! Published in 2017 at "Acta cirurgica brasileira"
DOI: 10.1590/s0102-865020170030000001
Abstract: Purpose: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model. Methods: Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal… read more here.
Keywords: correlation; sepsis model; abdominal sepsis; micro pet ... See more keywords
The Host CYP1A1-Microbiota Metabolic Axis Promotes Gut Barrier Disruption in Methicillin-Resistant Staphylococcus aureus-Induced Abdominal Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.802409
Abstract: Background Host-microbiota crosstalk has been implicated in multiple host metabolic pathway axes that regulate intestinal barrier function. Although constitutive cytochrome P4501A1 (CYP1A1) expression perturbs the microbiome-derived autoregulatory loop following enteric infection, little is known about… read more here.
Keywords: cyp1a1; microbiota; abdominal sepsis; host ... See more keywords
The Impact of TRAIL on the Immunological Milieu during the Early Stage of Abdominal Sepsis
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15061773
Abstract: Simple Summary Sepsis is the leading cause of morbidity and mortality worldwide. It reflects a deficiency in the interplay between the innate and adaptive immune response and leads to an injury of the body’s own… read more here.
Keywords: sepsis; trail; apoptosis; abdominal sepsis ... See more keywords
[Predictive value of red cell distribution width on the prognosis of patients with abdominal sepsis].
Sign Up to like & getrecommendations! Published in 2018 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.issn.2095-4352.2018.03.008
Abstract: OBJECTIVE To approach the value of red cell distribution width (RDW) on the prognostic assessment of patients with abdominal sepsis. METHODS The clinical data of adult patients with abdominal sepsis admitted to intensive care unit… read more here.
Keywords: apache score; value; patients abdominal; abdominal sepsis ... See more keywords