Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate
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DOI: 10.1002/cpt.1296
Abstract: Abemaciclib, an inhibitor of cyclin dependent kinases 4 and 6, is indicated for metastatic breast cancer treatment. Reversible increases in serum creatinine levels of ~15–40% over baseline have been observed following abemaciclib dosing. This study… read more here.
Keywords: filtration; glomerular filtration; abemaciclib inhibits; filtration rate ... See more keywords