Developing ABEmax-NG with Precise Targeting and Expanded Editing Scope to Model Pathogenic Splice Site Mutations In Vivo
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DOI: 10.1016/j.isci.2019.05.008
Abstract: Summary RNA splicing is related to many human diseases; however, lack of efficient genetic approaches to modulate splicing has prevented us from dissecting their functions in human diseases. Recently developed base editors (BEs) offer a… read more here.
Keywords: splice; developing abemax; scope; abemax precise ... See more keywords