Cellular glycosylation senses metabolic changes and modulates cell plasticity during epithelial to mesenchymal transition
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24553
Abstract: Epithelial to mesenchymal transition (EMT) is a developmental program reactivated by tumor cells that leads to the switch from epithelial to mesenchymal phenotype. During EMT, cells are transcriptionally regulated to decrease E‐cadherin expression while expressing… read more here.
Keywords: mesenchymal transition; aberrant glycosylation; cellular glycosylation; glycosylation ... See more keywords
Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-0761-1
Abstract: Glycosylation, the enzymatic attachment of carbohydrates to proteins and lipids, regulates nearly all cellular processes and is critical in the development and function of the nervous system. Axon pathfinding, neurite outgrowth, synaptogenesis, neurotransmission, and many… read more here.
Keywords: mortem brain; aberrant glycosylation; post mortem; glycosylation schizophrenia ... See more keywords
Targeting Tumor Glycans for Cancer Therapy: Successes, Limitations, and Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030645
Abstract: Simple Summary Aberrant glycosylation is a common feature of many cancers, and it plays crucial roles in tumor development and biology. Cancer progression can be regulated by several physiopathological processes controlled by glycosylation, such as… read more here.
Keywords: cancer; tumor; aberrant glycosylation; therapy ... See more keywords