The presence of aberrant p53 pattern is a negative prognostic predictor in squamous cell carcinoma of the nasal vestibule
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DOI: 10.1007/s00405-017-4659-8
Abstract: The aim of this study was to analyze the role of Ki-67, p53, and the “aberrant p53 pattern” in squamous cell carcinomas of the nasal vestibule. Patients between 1995 and 2014 were included. Baseline characteristics… read more here.
Keywords: nasal vestibule; p53 pattern; squamous cell; aberrant p53 ... See more keywords
Aberrant p53 immunostaining patterns in breast carcinoma of no special type strongly correlate with presence and type of TP53 mutations
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DOI: 10.1007/s00428-024-03897-3
Abstract: Recent studies have revealed an association between TP53 mutations and endocrine resistance in hormone receptor-positive, HER2-negative breast cancer (HR + HER2 −BC). Aberrant p53 immunostaining (IHC) patterns may provide a surrogate marker for TP53 mutations. Building upon… read more here.
Keywords: tp53 mutations; p53 immunostaining; type; aberrant p53 ... See more keywords
CD5 positivity and aberrant P53 expression predict primary refractoriness to first-line pola-R-CHP in patients with diffuse large B-cell lymphoma
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DOI: 10.1182/blood-2025-1887
Abstract: Background: The Pola-R-CHP regimen has emerged as an effective initial treatment for patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL). Nevertheless, a subset of patients demonstrates suboptimal responses. Identifying risk factors for primary refractoriness… read more here.
Keywords: treatment; cd5 positivity; pola; aberrant p53 ... See more keywords
Clinicopathological Characteristics of Advanced Epstein–Barr Virus-associated Gastric Cancer Highlighting Aberrant p53 Expression
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DOI: 10.21873/anticanres.16002
Abstract: Background/Aim: Epstein–Barr virus (EBV)-associated gastric cancer is a distinct subtype of stomach adenocarcinoma. Although previous studies have investigated its clinicopathological characteristics, there is a lack of research focusing on advanced EBV-associated gastric cancer. In this… read more here.
Keywords: ebv associated; associated gastric; gastric cancer; aberrant p53 ... See more keywords