Articles with "aberrantly methylated" as a keyword



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Identification of aberrantly methylated differentially expressed genes and associated pathways in endometrial cancer using integrated bioinformatic analysis

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Published in 2020 at "Cancer Medicine"

DOI: 10.1002/cam4.2956

Abstract: Endometrial cancer (EC) is a fatal female reproductive tumor. Bioinformatic tools are increasingly developed to screen out molecular targets related to EC. In this study, GSE17025 and GSE40032 were obtained from Gene Expression Omnibus (GEO).… read more here.

Keywords: analysis; identification aberrantly; aberrantly methylated; endometrial cancer ... See more keywords
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Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28904

Abstract: Abnormal DNA methylation has been demonstrated to drive breast cancer tumorigenesis. Thus, this study aimed to explore differentially expressed biomarkers driven by aberrant methylation in breast cancer and explore potential pathological mechanisms using comprehensive bioinformatics… read more here.

Keywords: identification aberrantly; aberrantly methylated; breast cancer; bioinformatics analysis ... See more keywords

Identification of Seven Aberrantly Methylated and Expressed Genes in Adrenocortical Carcinoma

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Published in 2019 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2019.00472

Abstract: Background: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with an unfavorable prognosis and limited treatment options. Nevertheless, no clinically applicable molecular markers have been identified for the progression of ACCs. DNA methylation alterations were… read more here.

Keywords: adrenocortical carcinoma; aberrantly methylated; abnormally methylated; expressed genes ... See more keywords

Integrated Bioinformatics Analysis Reveals the Aberrantly Methylated Differentially Expressed Genes in Dilated Cardiomyopathy

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Published in 2024 at "International Journal of Medical Sciences"

DOI: 10.7150/ijms.92537

Abstract: Dilated cardiomyopathy (DCM) causes heart failure and sudden death. Epigenetics is crucial in cardiomyopathy susceptibility and progression; however, the relationship between epigenetics, particularly DNA methylation, and DCM remains unknown. Therefore, this study identified aberrantly methylated… read more here.

Keywords: aberrantly methylated; dilated cardiomyopathy; differentially expressed; methylated differentially ... See more keywords