Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13374
Abstract: Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity-dependent labeling (PDL) with biotin followed… read more here.
Keywords: abi1; role; ripk1; regulation ... See more keywords
Abstract 3725: ABI1 regulates STAT3 transcription through a DNA binding activity
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3725
Abstract: Prostate cancer (PCa) is characterized by the complexity of oncogenic signaling and heterogeneity of transcriptional landscapes. Adaptor protein ABI1 is a tumor suppressor in PCa, as evidenced by its loss or downregulation in high-grade and… read more here.
Keywords: abi1; dna; transcription; dna binding ... See more keywords