Articles with "abietane" as a keyword



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Quinone diterpenes from Salvia species: chemistry, botany, and biological activity

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Published in 2019 at "Phytochemistry Reviews"

DOI: 10.1007/s11101-019-09633-z

Abstract: A total of 175 abietane quinone diterpenes with ortho- or para-quinone chromophore, namely 11,12-ortho-quinone abietane, 11,14-para-quinone abietane, seco-abietane and abeo-abietanes quinones were surveyed from 130 species of Salvia of central Asia/Mediterranean area, eastern Asia, and… read more here.

Keywords: botany; quinone; chemistry; abietane ... See more keywords

Structurally diversified ent-kaurane and abietane diterpenoids from the stems of Tripterygium wilfordii and their anti-inflammatory activity.

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Published in 2021 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2021.105178

Abstract: Four undescribed ent-kaurane diterpenoids, wilkaunoids A - D (1-4), and three undescribed abietane diterpenoids, wilabinoids A - C (13-15), along with thirteen known ones (5-12 and 16-20), were isolated from Tripterygium wilfordii. Their structures were elucidated by extensive spectroscopic… read more here.

Keywords: anti inflammatory; abietane; abietane diterpenoids; ent kaurane ... See more keywords

CYP76 Oxidation Network of Abietane Diterpenes in Lamiaceae Reconstituted in Yeast.

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Published in 2019 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.9b00714

Abstract: Rosemary and sage species from Lamiaceae contain high amounts of structurally related but diverse abietane diterpenes. A number of substances from this compound family have potential pharmacological activities and are used in the food and… read more here.

Keywords: cyp76 oxidation; oxidation network; abietane; abietane diterpenes ... See more keywords

Ferroptosis Inhibitory Aromatic Abietane Diterpenoids from Ajuga decumbens and Structural Revision of Two 3,4-Epoxy Group-Containing Abietanes.

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Published in 2022 at "Journal of natural products"

DOI: 10.1021/acs.jnatprod.2c00352

Abstract: Two new 3,4-epoxy group-containing abietane diterpenoids (1 and 2), together with five known diterpenoids (3-7), were isolated from Ajuga decumbens. Their structures were elucidated by spectroscopic data analysis, NMR calculations, and X-ray diffraction experiments. The… read more here.

Keywords: epoxy group; group containing; ajuga decumbens; abietane diterpenoids ... See more keywords

Euphohelides A-C, ent-Abietane-Type Norditerpene Lactones from Euphorbia helioscopia and Their Anti-Inflammatory Activities.

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Published in 2023 at "Journal of natural products"

DOI: 10.1021/acs.jnatprod.3c00041

Abstract: Three unreported ent-abietane-type norditerpene lactones, euphohelides A-C (1-3), and 11 known analogs (4-14) were isolated from the whole plants of Euphorbia helioscopia L. Euphohelide A (1) is an unprecedented 2-nor-ent-abietane lactone bearing a unique 5/6/6/5… read more here.

Keywords: ent abietane; type norditerpene; euphorbia helioscopia; norditerpene lactones ... See more keywords

Sustainable leads for hypoxic tumor therapy: allosteric selective inhibition of carbonic anhydrase IX by abietane-type resin acids

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Published in 2025 at "RSC Advances"

DOI: 10.1039/d5ra05372b

Abstract: Carbonic anhydrase IX (CA IX) helps hypoxic tumors maintain the acidic extracellular milieu that drives invasion and therapy resistance, making it an attractive but still under-exploited drug target. Here we report that four abietane-type resin… read more here.

Keywords: carbonic anhydrase; resin acids; abietane; type resin ... See more keywords

High Yield of Bioactive Abietane Diterpenes in Salvia sclarea Hairy Roots by Overexpressing Cyanobacterial DXS or DXR Genes.

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Published in 2019 at "Planta medica"

DOI: 10.1055/a-0895-5878

Abstract: Abietane diterpenoids, containing a quinone moiety, are synthesized in the roots of several Salvia species. Promising cytotoxicity and antiproliferative activities have been reported for these compounds in various cell and animal models. We have recently… read more here.

Keywords: hairy roots; deoxy xylulose; abietane; xylulose phosphate ... See more keywords