A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
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DOI: 10.1016/j.fitote.2020.104484
Abstract: The Src-homology 2 domain-containing phosphatase 2 (SHP2), encoded by PTPN11, has been reported oncogenic tyrosine phosphatase associated with various tumors and played critical roles in many cell signaling events. Targeting SHP2 by small molecules may… read more here.
Keywords: shp2; ajuga ovalifolia; abietane diterpenoid; var calantha ... See more keywords
New abietane diterpenoid glucosides from underground parts of Isodon taliensis
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DOI: 10.1080/10286020.2018.1518321
Abstract: Abstract Two new abietane diterpenoid glucosides, talienosides A and B (1 and 2), along with four known compounds (3 – 6), were isolated from the ethyl acetate soluble portion of 70% acetone extract of the underground parts… read more here.
Keywords: underground parts; abietane diterpenoid; new abietane; diterpenoid glucosides ... See more keywords
A new abietane diterpenoid from the roots of Tripterygium regelii
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DOI: 10.1080/14786419.2017.1416379
Abstract: Abstract A new abietane diterpenoid, tripterregeline A (1), together with six known diterpenoids (2–7), were isolated from the roots of Tripterygium regelii. The structure of 1 was elucidated by extensive spectroscopic methods and the known… read more here.
Keywords: new abietane; abietane diterpenoid; tripterygium regelii; roots tripterygium ... See more keywords
A new abietane diterpenoid glycoside from ajuga ovalifolia var. calantha
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Research"
DOI: 10.1080/14786419.2018.1500574
Abstract: Abstract A new abietane diterpenoid glycoside, ajugaside B (1), along with three known compounds (2–4), were isolated from the whole plants of Ajuga ovalifolia var. calantha. The structure of the new compound (1) was elucidated… read more here.
Keywords: ajuga ovalifolia; abietane diterpenoid; var calantha; diterpenoid glycoside ... See more keywords