Role of c-Abl-GSK3&bgr; Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction
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DOI: 10.1093/toxsci/kfy155
Abstract: Impairment in autophagy-lysosomal pathway (ALP) results in accumulation of misfolded proteins and dysfunctional organelles, which is the hallmark of neurodegenerative diseases including Parkinson's disease (PD). Recent studies revealed activated nonreceptor tyrosine kinase Abelson (c-Abl) in… read more here.
Keywords: mpp induced; abl gsk3; autophagy lysosomal; gsk3 ... See more keywords