Articles with "abl1 like" as a keyword



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BCR/ABL1–like acute lymphoblastic leukemia: How to diagnose and treat?

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Published in 2019 at "Cancer"

DOI: 10.1002/cncr.31848

Abstract: BCR/ABL1–like acute lymphoblastic leukemia (ALL) accounts for 15% to 30% of B‐lineage ALL, with a peak of incidence occurring in adolescence. This subgroup of patients is characterized by a peculiar transcriptional profile that resembles that… read more here.

Keywords: bcr; abl1 like; lymphoblastic leukemia; acute lymphoblastic ... See more keywords
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Successful Use of Nilotinib in the Therapy of a Patient with a Chemoresistant Relapse of BCR-ABL1-Like Phenotype Acute Lymphoblastic Leukemia

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Published in 2018 at "Oncology Research and Treatment"

DOI: 10.1159/000490121

Abstract: Introduction: Relapse of acute lymphoblastic leukemia (ALL) after allogeneic hematopoietic cell transplantation (HCT) is a therapeutic challenge. We present the case of a 20-year-old patient with a relapse of Philadelphia chromosome-negative ALL B-common over 2… read more here.

Keywords: abl1 like; relapse; therapy; bcr abl1 ... See more keywords
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BCR/ABL1-Like Acute Lymphoblastic Leukemia: From Diagnostic Approaches to Molecularly Targeted Therapy.

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Published in 2021 at "Acta haematologica"

DOI: 10.1159/000519782

Abstract: BACKGROUND BCR/ABL1-like acute lymphoblastic leukemia is a newly recognized high-risk subtype of ALL, characterized by the presence of genetic alterations activating kinase and cytokine receptor signaling. This subtype is associated with inferior outcomes, compared to… read more here.

Keywords: abl1 like; lymphoblastic leukemia; acute lymphoblastic; like acute ... See more keywords
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The Validation of the BCR/ABL1-like Predictor across Laboratories Shows Reproducibility of Results

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Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-122116

Abstract: Background BCR/ABL1-like (alias Ph-like) acute lymphoblastic leukemia (ALL) is a clinically challenging subgroup. Its incidence varies from 10% in children to 30% in adult ALL. The underlying genomic background, usually characterized by the presence of… read more here.

Keywords: board directors; abl1 like; membership entity; directors advisory ... See more keywords
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Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.13492

Abstract: Approximately 15% of pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by gene expression similar to that of BCR-ABL1-positive disease and unfavorable prognosis. This BCR-ABL1-like subtype shows a high frequency of B-cell development… read more here.

Keywords: fusion; tyrosine kinase; abl1 like; bcr abl1 ... See more keywords
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BCR-ABL1-like acute lymphoblastic leukemia in childhood and targeted therapy.

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Published in 2020 at "Haematologica"

DOI: 10.3324/haematol.2018.207019

Abstract: Material published in Haematologica is covered by copyright. All rights are reserved to the Ferrata Storti Foundation. Use of published material is allowed under the following terms and conditions: https://creativecommons.org/licenses/by-nc/4.0/legalcode. Copies of published material are… read more here.

Keywords: abl1 like; published material; material; like acute ... See more keywords