Relatively favorable outcome after allogeneic stem cell transplantation for BCR‐ABL1‐positive AML: A survey from the acute leukemia working party of the European Society for blood and marrow transplantation (EBMT)
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DOI: 10.1002/ajh.24928
Abstract: The aim of the study was to assess the role of allogeneic stem cell transplantation (SCT) in patients diagnosed with BCR‐ABL1‐positive acute myeloid leukemia (AML). Fifty‐seven patients (median age, 48 years, range: 19‐67) with BCR‐ABL1… read more here.
Keywords: abl1 positive; positive aml; transplantation; sct ... See more keywords
Refined risk stratification helps guiding transplantation choice in adult BCR::ABL1-positive acute lymphoblastic leukemia
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DOI: 10.1038/s41408-024-01055-1
Abstract: Dear Editor, The integration of tyrosine kinase inhibitors (TKIs) into multiagent chemotherapy regimens has markedly improved the prognosis of BCR::ABL1 -positive acute lymphoblastic leukemia ( BCR::ABL1 + ALL). Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains… read more here.
Keywords: abl1 positive; risk; leukemia; bcr ... See more keywords
Improved Survival outcomes with allo-HSCT in NUP214::ABL1-Positive Acute leukemia: A pooled analysis and single-center experience
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DOI: 10.1182/blood-2025-4258
Abstract: Introduction The NUP214::ABL1 fusion gene, resulting from the fusion of nucleoporin NUP214 and the tyrosine kinase ABL1, harbors kinase activity similar to that of BCR::ABL1 and acts as an oncogenic driver in acute leukemia (AL).… read more here.
Keywords: abl1 positive; allo hsct; nup214 abl1; group ... See more keywords