Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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DOI: 10.1158/0008-5472.can-22-0834
Abstract: Comprehensive proteogenomic and in silico analyses of a vast number of VUSs identify a novel set of oncogenic and druggable mutations in the well-characterized RET oncogene. read more here.
Keywords: calcium binding; ablating mutations; induce constitutive; mutations induce ... See more keywords