Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol-induced cell death and heart failure
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DOI: 10.3892/ijmm.2022.5216
Abstract: CXCR4 is a seven-transmembrane-spanning Gi-coupled receptor for the SDF-1 chemokine and plays a critical role in cardiovascular development and post-injury repair. However, the specific role of CXCR4 in cardiomyocytes is incompletely understood. It was hypothesized… read more here.
Keywords: cxcr4 expression; ablation cxcr4; mhc cre; cxcr4 ... See more keywords