Focal and generalized seizure activity after local hippocampal or cortical ablation of NaV1.1 channels in mice
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DOI: 10.1111/epi.16482
Abstract: Early onset seizures are a hallmark of Dravet syndrome. Previous studies in rodent models have shown that the epileptic phenotype is caused by loss‐of‐function of voltage‐gated NaV1.1 sodium channels, which are chiefly expressed in γ‐aminobutyric… read more here.
Keywords: ablation nav1; ablation; nav1 channels; seizure ... See more keywords