Highly sensitive fluorescent bioassay of 2,3,7,8-tetrachloro-dibenzo-p-dioxin based on abnormal expression of cytochrome P450 1A2 in human cells.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.08.006
Abstract: Current in vitro bioassays of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, a major threat carcinogen) are relied on murine cells and fluorescent probe 7-ethoxyresorufin (7-ER), in which TCDD mostly causes abnormal expression of cytochrome P450 1A1 (CYP1A1). However, for human… read more here.
Keywords: abnormal expression; expression; expression cytochrome; cytochrome p450 ... See more keywords
Abnormal expression of Nrf2 may play an important role in the pathogenesis and development of adenomyosis
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DOI: 10.1371/journal.pone.0182773
Abstract: Objective To explore the expression level of Nrf2 in adenomyosis and study the mechanism of abnormal expression of Nrf2 in the pathogenesis of adenomyosis. Methods Western blot, immunohistochemistry(IHC) and real time PCR were used to… read more here.
Keywords: adenomyosis; expression nrf2; pathogenesis; abnormal expression ... See more keywords
[Environmental chemicals exposure and abnormal expression of non-coding RNAs].
Sign Up to like & getrecommendations! Published in 2019 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.issn.0253-9624.2019.05.003
Abstract: Environmental chemicals exposure is closely related to occurrence and development of diseases. The abnormal expression of non-coding RNAs is a key factor in biological effects of environmental chemicals. Non-coding RNAs play an important role in… read more here.
Keywords: coding rnas; chemicals exposure; abnormal expression; non coding ... See more keywords