Chlamydia abortus OmcB protein is essential for adhesion to host cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of basic microbiology"
DOI: 10.1002/jobm.202100312
Abstract: Chlamydia abortus (C. abortus) is one of the most important zoonotic pathogens, causing a number of serious diseases. The adhesion of C. abortus to host cells is the first and crucial step in the process… read more here.
Keywords: abortus; omcb protein; omcb; host cells ... See more keywords
Genomic and Immunoinformatics Insights Into a Bovine‐Derived Brucella abortus S19 Field Strain: Adaptations Impacting Vaccine Efficacy
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.70593
Abstract: ABSTRACT Brucella abortus S19 is a widely used live attenuated vaccine strain for bovine brucellosis control; however, its long‐term efficacy is challenged by genomic plasticity and adaptive mechanisms. This study presents a comprehensive comparative genomic… read more here.
Keywords: abortus; efficacy; brucella abortus; abortus s19 ... See more keywords
Detection of Brucella abortus by immunofluorescence assay using anti-16-kDa outer membrane protein (OMP16) antibody
Sign Up to like & getrecommendations! Published in 2017 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-017-2529-9
Abstract: Brucellosis in humans is one of the most important zoonotic diseases worldwide. This disease causes weakness, fever, pain, sweats, and complications in the liver, spleen, and lymphatic system; Brucellosis requires long-term antibiotic therapy. This study… read more here.
Keywords: protein; antibody; outer membrane; abortus ... See more keywords
Nocodazole treatment interrupted Brucella abortus invasion in RAW 264.7 cells, and successfully attenuated splenic proliferation with enhanced inflammatory response in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2016.11.028
Abstract: Brucellosis is one of the most important and widespread zoonosis worldwide responsible for serious economic losses and considerable public health burden. In this study, we investigated the modulatory effect of a microtubule-inhibitor, nocodazole, on B. abortus… read more here.
Keywords: brucella; invasion; abortus; mice ... See more keywords
The inhibitory effect of flavonoids and their gut-derived metabolites on the replication of Chlamydia abortus in the AH-1 ovine trophoblast cell line.
Sign Up to like & getrecommendations! Published in 2019 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2019.09.006
Abstract: The obligate intracellular bacterium Chlamydia abortus causes abortion and constitutes a worldwide threat for livestock. Plant-derived flavonoids have antimicrobial effects against veterinary and human pathogens and may be of help in the fight against C.… read more here.
Keywords: chlamydia abortus; derived metabolites; abortus; ovine trophoblast ... See more keywords
Evaluation of protective and immune responses following vaccination with recombinant MIP and CPAF from Chlamydia abortus as novel vaccines for enzootic abortion of ewes.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.06.088
Abstract: MIP and CPAF from Chlamydia have been shown to be effective in inducing immune responses important in clearing chlamydial infections. This study evaluates the protection conferred by MIP and CPAF as novel vaccines in pregnant… read more here.
Keywords: novel vaccines; mip cpaf; abortus; cpaf ... See more keywords
A combined subunit vaccine comprising of BP26, Omp25 and L7/L12 against brucellosis.
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens and disease"
DOI: 10.1093/femspd/ftaa002
Abstract: The current vaccines against brucellosis namely Brucella abortus strain 19 and RB51, prevent infection in animals but pose potential risks like virulence and attenuation reversal. In this milieu, although subunit vaccination using a single potent… read more here.
Keywords: combined subunit; omp25 l12; subunit vaccine; abortus ... See more keywords
Brucella abortus induces dynamin-related protein 1 (DRP1)-dependent mitochondrial fission in infected macrophages via stress sensor IRE1α altering metabolic function.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of immunology"
DOI: 10.1093/jimmun/vkaf198
Abstract: Brucella abortus exploits the endoplasmic reticulum as a site for replication, triggering the unfolded protein response (UPR). While various pathogens have developed strategies to manipulate mitochondrial dynamics, the mechanisms underlying bacterial infection and mitochondrial dynamics… read more here.
Keywords: abortus; mitochondrial fission; protein; brucella ... See more keywords
Immunization with a combination of recombinant Brucella abortus proteins induces T helper immune response and confers protection against wild‐type challenge in BALB/c mice
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14015
Abstract: Protective efficiency of a combination of four recombinant Brucella abortus (B. abortus) proteins, namely, ribosomal protein L7/L12, outer membrane protein (OMP) 22, OMP25 and OMP31, was evaluated as a combined subunit vaccine (CSV) against B.… read more here.
Keywords: abortus; recombinant brucella; csv; brucella ... See more keywords
Histidine auxotroph mutant is defective for cell separation and allows the identification of crucial factors for cell division in Brucella abortus
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Microbiology"
DOI: 10.1111/mmi.14956
Abstract: The pathogenic bacterium Brucella abortus invades and multiplies inside host cells. To grow inside host cells, B. abortus requires a functional histidine biosynthesis pathway. Here, we show that a B. abortus histidine auxotroph mutant also… read more here.
Keywords: abortus; cell division; brucella abortus; histidine auxotroph ... See more keywords
Isolation of Brucella abortus from a Dog and a Cat Confirms their Biological Role in Re‐emergence and Dissemination of Bovine Brucellosis on Dairy Farms
Sign Up to like & getrecommendations! Published in 2017 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.12535
Abstract: Brucellosis is highly contagious bacterial zoonoses affecting a wide range of domesticated and wild animals. In this study, Brucella (B.) abortus bv 1 was identified in uterine discharge of apparently healthy bitch and queen with… read more here.
Keywords: brucella; isolation brucella; abortus; role ... See more keywords