Inhibitor Discovery by Convolution ABPP.
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DOI: 10.1007/978-1-4939-6439-0_4
Abstract: Activity-based protein profiling (ABPP) has emerged as a powerful proteomic approach to study the active proteins in their native environment by using chemical probes that label active site residues in proteins. Traditionally, ABPP is classified… read more here.
Keywords: convolution abpp; inhibitor discovery; abpp; discovery convolution ... See more keywords
Advanced Activity-Based Protein Profiling Application Strategies for Drug Development
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DOI: 10.3389/fphar.2018.00353
Abstract: Drug targets and modes of action remain two of the biggest challenges in drug development. To address these problems, chemical proteomic approaches have been introduced to profile targets in complex proteomes. Activity-based protein profiling (ABPP)… read more here.
Keywords: drug development; based protein; abpp; activity based ... See more keywords